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Knock Out Rat Consortium


Dnah11Tn(sb-T2/Bart3)2.293Mcwi

Insertion Overview
UCSC Blat Alignment
Insertion Location:intron 25
5' Flanking Sequence: TACATACATGCAGGCAAAATACTCATACAGTAAAAATTAGAAATTAAGCA
AAACCCTAAGTACGTTAAAACATTTTGAGGGTACACAAGTTATCTCTTGC
ACAGTGCTActag
Gene
***Rat Entrez Gene If Available; Else Human or Mouse
Symbol:Dnah11
Name:dynein, axonemal, heavy chain 11
Synonyms:Dnahc11
Chromosome:N/A
Mouse Allele
MGISymbolNameType
MGI:1856917Dnahc11ivsitus inversus viscerumSpontaneous
MGI:3623683Dnahc11tm1.1Bknrtargeted mutation 1.1, Martina BruecknerTargeted (Reporter)
MGI:3623682Dnahc11tm1Bknrtargeted mutation 1, Martina BruecknerTargeted (knock-out)
MGI:2152963Dnahc11tm1Ssptargeted mutation 1, S Steven PotterTargeted (knock-out)
Associated Diseases
DiseaseDisease ClassSub Category
Ciliary DyskinesiaRespiratoryMucosal Inflammation
Kartagener SyndromeRespiratoryDevelopmental, Situs Inversus Viscerum
Gene Ontology Function Process Component
GOTermEvidencePubmed
GO:0000166nucleotide bindingIEA
GO:0003674molecular_functionND
GO:0003777microtubule motor activityIEA
GO:0003777microtubule motor activityISS
GO:0004197cysteine-type endopeptidase activityIEA
GO:0005524ATP bindingIEA
GO:0016887ATPase activityIEA
Homologene Orthology (Human/Mouse)
TaxonSymbolSynonymsChromosome
humanDNAH11CILD7|DNAHBL|DNAHC11|DNHBL|DPL11|FLJ30095|FLJ37699N/A
mouseDnahc11iv|lrdN/A
Related Links
TaxonDatabaseIdentifier
ratEnsemblENSRNOG00000005451
ratRGD621088
humanEnsemblENSG00000105877
humanHGNC2942
humanHPRD09134
humanMIM603339
mouseEnsemblENSMUSG00000018581
mouseMGIMGI:1100864
Rat Model Source
Medical College of Wisconsin