December 2009 eNews - SCID, piggyBac, Featured Models

December 2009's eNews includes Transposagen's announcement of the World's First SCID Rat, the opportunity for your company or institution to sub-license the robust transposon technology called piggyBac, and our list of Featured TKO™ Knockout Rat Models.

Please forward Transposagen's eNews to your colleagues that are interested in information on the creation of the newest TKO™ Knockout Rat Models. For more information, email info@transposagenbio.com or call 859-428-8561.

Transposagen Offers World's First SCID Rat

Transposagen has characterized the world's first rat model of severe combined immunodeficiency, or SCID. The TKO™ SCID Rat Model can be used for transplantation and immunology studies.

"We now have intellectual property covering the SCID phenotype in rat and will be offering the SCID rat and other rat models of the immune system in the near future," said Dr. Eric Ostertag, CEO of Transposagen. "This new immune deficiency rat model cannot reject transplanted tissues, even from other species, and will be especially important in cancer and transplantation research."

piggyBac Technology Sub-licenses Available

piggyBac is a highly versatile technology that is used for genetic engineering in almost any animal, allowing for both mutagenesis and transgenesis and is a core technology used by Transposagen to create a large variety of TKO™ Knockout Rat Models.

piggyBac has other applications including reprogramming various somatic cells to create induced pluripotent stem (iPS) cells. These non-embryonic stem cells share most of the therapeutic promise of embryonic stem cells, without having the ethical dilemmas.

If you have an interest in sub-licensing piggyBac technology, please contact Transposagen. Academic researchers - ask about a free research license or get plasmids with a standard Material Transfer Agreement (MTA).

Featured TKO™ Knockout Rat Models

To view the database of TKO™ Knockout Rat Models - CLICK HERE. These models are in various stages of phenotyping. Associated diseases are predicted.